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What is Subutex?

Subutex contains buprenorphine as its essential component that works as an opioid medication to treat moderate to severe chronic or acute pain and opioid dependence. 

It helps to bind and activate opioid receptors in the brain and nervous system to reduce pain sensations in the body. 

Important Information

  • Subutex is prescribed as an additional treatment with physical therapies to treat pain and opioid disorder.
  • You can take Subutex in various forms, such as sublingual tablets, buccal films, intravenous injection, implant, transdermal skin patch, etc. 
  • It is one of the highly addictive medicines; therefore, it is advisable to keep track of your medicine and never share it with anyone, especially those with a history of drug abuse or addiction.
  • It is also advisable to take frequent medical tests while using Subutex; please consult your doctor regarding this.
  • You can buy Subutex online or offline only if you hold an appropriate prescription, as buying or selling Subutex without a proper prescription is prohibited under the law, and authorities may hold you liable for punishment if you do so.

What to know before taking Subutex?

Using Subutex without medical advice can be dangerous. It works by activating opioid receptors in the brain and nervous system to reduce pain signals. 

To let the medicine work more effectively, you should take all the necessary precautions while taking medicine. 

In addition to above all, you need to consider the following things before starting your treatment with Subutex:

  • Using Subutex can be dangerous for your health if you are allergic to it or any of its components or other similar medicines. 
  • Subutex is a dangerous medicine; therefore, you should avoid taking Subutex if you are suffering from the following health disorders or history thereof:
    • Breathing disorder 
    • Sleep apnea (breathing that stops while sleeping)
    • Abnormal spine curvature that affects your breathing 
    • Damaged liver (hepatitis B or C)
    • Kidney disorder 
    • Enlarged prostate gland 
    • Urination problems 
    • Head injuries or brain tumor 
    • Hallucinations 
    • Mental illness 
    • Thyroid disorder 
    • Stomach problems 
    • Problems with gallbladder and adrenal gland
  • Expecting women and lactating and breastfeeding mothers should avoid taking Subutex; it can harm their children and make them dependent on the medicine. 
  • You should avoid taking Subutex if you have recently taken any MAO inhibitors.
  • Abrupt medication withdrawal can adversely affect your health; you should consult your doctor before leaving Subutex. Your doctor will gradually decrease your medicine dose to avoid withdrawal symptoms.
  • You should consult your physician to learn more about the risks and benefits associated with Subutex.

How to take Subutex?

Subutex should be taken as advised by your doctor because it is highly addictive and habit-forming and can adversely affect your health if taken inappropriately. 

To avoid other dangerous consequences of using Subutex, you should follow all the necessary precautions while taking it. 

We also advise you to tell your doctor if you are not observing any improvement in your health condition.

Subutex dosage

Subutex is an opioid pain medication and effective treatment for moderate to severe pain and opioid dependence. 

Therefore, it is a dangerous medication; you should consult your doctor for the correct and suitable Subutex dosage.  

Your physician will examine you thoroughly before prescribing you suitable medicine dosages. Doctors generally consider the following things before prescribing you appropriate medicine dosages:

  • Age of the patient 
  • Weight of the patient 
  • The medical condition of the patient 

The following are the usual Subutex dosage that your doctor can prescribe you:

Dosage for treating severe pain 

In the buccal dosage form 

  • For adults 

75 mcg of Subutex buccal film, as a single dose, or after every 12 hours for four days

  • For children 

Using Subutex for treating pain in children is risky; therefore, you should consult your doctor before giving it to your child. 

Dosage for treating and managing opioid withdrawal 

In the form of oral tablets

  • For adults 

4 mg to 24 mg of the medicine orally, once a day, or as advised by the doctor

  • For children 

Using Subutex for treating and manage opioid withdrawal in children is not recommended.


Subutex is a first-choice treatment for moderate to severe pain but can cause an overdose if taken in excess. The Subutex overdose looks like the following and causes the following overdose symptoms:

  • Dizziness or drowsiness 
  • Weakness 
  • Cold and clammy skin
  • Pinpoint pupils 
  • Slow heart rate
  • Weak pulse rate
  • Breathlessness 
  • Coma 

We never advise you to ignore these fatal overdose symptoms. You should therefore consult your doctor ASAP if an overdose happens. You can also seek emergency medical help by calling the poison helpline at 1-800-222-1222.

What to avoid while using Subutex?

Taking alcohol while using Subutex is not safe; it can adversely affect your health. 

Subutex intends to impair your thinking and reactions and cause you severe dizziness and drowsiness. Therefore, you should avoid driving and performing other activities that require you to be alert and attentive. 

Before taking any herbal products, vitamins, and other nutritional supplements while using Subutex, please consult your doctor. 

Subutex side effects

Although Subutex is a safe and effective medication used in pain management, still it can cause some of the following side effects:

  • Constipation 
  • Nausea or vomiting 
  • Headache 
  • Unusual sweating 
  • Sleeplessness 
  • Bodice 

These mild side effects don’t need much medical attention; however, you should immediately consult your doctor if they are unbearable or bothering you too much. 

You should also stop taking Subutex and take medical assistance if you experience the following health disorders:

  • Symptoms of opioid withdrawal such as goosebumps, shivering, pain in the muscles, unusual sweating, watery eyes, runny nose
  • Noisy breathing 
  • Sighing 
  • Slow or shallow breathing 
  • Sleep apnea (breathing that stops while sleeping)
  • Slow heartbeats 
  • Weak pulse rate 
  • Lightheadedness 
  • Pain in the chest 
  • Difficulty in breathing 
  • Low cortisol level in the body resulting in loss of appetite, nausea, vomiting, weakness, tiredness, dizziness
  • Symptoms of the damaged liver pain in the upper stomach, nausea, loss of appetite, dark-colored urine, clay-colored stools, itchiness, jaundice 
  • Symptoms of serotonin syndrome such as hallucinations, agitation, sweating, fever, shivering, fast heart rate, twitching, stiff muscles, nausea, vomiting, diarrhea, loss of coordination 
  • Any other severe allergic reactions to the medicine

What drugs can interact with Subutex?

Subutex tends to interact with the following medicine and can dangerously affect your health:

  • Cold or allergy medication 
  • Medicines to treat asthma, chronic obstructive pulmonary disorders (COPD), and other breathing disorders 
  • Water pills 
  • Opioid pain medication 
  • Narcotic drugs 
  • Sedatives 
  • Sleeping pills 
  • Muscles relaxants
  • Medicines used for treating mood or behavioral disorders or other mental illnesses 
  • Stimulant 
  • Antidepressants
  • Medicines for treating Parkinson’s disorder and migraine headache 
  • Antibiotics 
  • Antifungal medications 
  • Medications used for maintaining blood pressure level 
  • Heart medication 
  • Antileisure medications 
  • Medicine to treat HIV or hepatitis C
  • Other over-the-counter medicines 

As the interaction of Subutex with these medicines can be life-threatening. Therefore you need to tell your health expert about all the medications and therapies before taking Subutex.